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Bacterial Genomes: Trees and Networks - cover image

Copyright

Aswin Sai Narain Seshasayee;

Published On

2025-02-28

ISBN

Paperback978-1-80511-495-6
Hardback978-1-80511-496-3
PDF978-1-80511-497-0
HTML978-1-80511-499-4
EPUB978-1-80511-498-7

Language

  • English

Print Length

254 pages (xvi+238)

Dimensions

Paperback178 x 21 x 254 mm(7.01" x 0.83" x 10")
Hardback178 x 38 x 254 mm(7.01" x 1.5" x 10")

Weight

Paperback605g (21.34oz)
Hardback820g (28.92oz)

Media

Illustrations38

THEMA

  • MFN
  • PSG
  • PSAJ
  • PSD

BISAC

  • SCI045000
  • SCI027000
  • SCI029000
  • SCI007000
  • SCI049000

Keywords

  • Bacterial Genomics
  • Microbial Evolution
  • Regulatory Networks
  • Microbial Adaptation
  • biochemical processes
  • Molecular Microbiology

Bacterial Genomes

Trees and Networks

Microbes form the “unseen majority” of life on Earth, with bacteria at the forefront as both the architects of life’s chemical foundations and agents of disease. But their story is far more complex. Bacteria thrive in diverse and extreme environments, driven by the dynamic evolution of their genomes. These tiny organisms wield an extraordinary ability to adapt, balancing genetic changes across generations with rapid physiological responses to environmental shifts.

In Bacterial Genomes, the evolutionary and regulatory processes that shape bacterial life are brought to life. This textbook offers a conceptual exploration of how bacterial genomes are organized, how they evolve, and how their genetic information is interpreted through intricate molecular networks. Drawing on both cutting-edge research and the historical milestones that shaped microbiology, it illuminates how bacteria navigate the intersection of genetic adaptation and ecological resilience.

Designed for college students, interdisciplinary researchers, and even the determined amateur, Aswin Seshasayee moves beyond technical jargon to provide a thought-provoking synthesis of bacterial evolution and adaptation. Unlike traditional genomics texts, this book blends historical insights with contemporary discoveries, offering a fresh perspective on the role of bacteria in shaping the living world.

Additional Resources

[document]EPUB Accessibility Report

Contents

Preface

(pp. 1–4)
  • Aswin Sai Narain Seshasayee

1. All creatures great and small

(pp. 5–32)
  • Aswin Sai Narain Seshasayee

2. The molecules of bacteria and of life

(pp. 33–64)
  • Aswin Sai Narain Seshasayee

3. The genome: how much DNA?

(pp. 65–106)
  • Aswin Sai Narain Seshasayee

4. The ebb and flow of bacterial genomes

(pp. 107–160)
  • Aswin Sai Narain Seshasayee

5. Reading and organising the genome

(pp. 161–218)
  • Aswin Sai Narain Seshasayee

Contributors

Aswin Sai Narain Seshasayee

(author)
Researcher and Associate Professor at National Centre for Biological Sciences
https://orcid.org/0000-0001-7028-1803
http://www.ncbs.res.in/aswin

Aswin Sai Narain Seshasayee is a researcher and Associate Professor at the National Centre for Biological Sciences (NCBS), a centre of Tata Institute of Fundamental Research (TIFR) in Bangalore, India. His lab is interested in fundamental aspects of the function and evolution of bacterial genomes and gene regulatory networks. His career in the sciences started off with a Bachelors of Technology at Anna University, Chennai, India, during which a lot of time left alone to explore and break things in the bioinformatics laboratory of Professor Gautam Pennathur and in the experimental microbiology and protein engineering laboratory of Professor Sankaran encouraged him to take up research for a career. He then pursued research as an intern, a PhD student and then briefly a postdoc with Nicholas Luscombe at EMBL-European Bioinformatics Institute, Hinxton, Cambridge, UK (and St John’s College and Girton College, University of Cambridge). He has been with NCBS since December 2010, his research here funded over the years by the Department of Atomic Energy (Govt of India) core support to TIFR and NCBS, Department of Biotechnology, Department of Science and Technology and Science and Engineering Research Board (all Govt of India), CEFIPRA and DBT-Wellcome Trust India Alliance. Beyond science, he enjoys making music, painting watercolour landscapes and reading classic crime and fantasy fiction and popular history.